Ordinary Shares, par value $0.0001 per share

BeOne Medicines Ltd.

c/o BeOne Medicines I GmbH, Basel, V8, 4051

The disclosures in the Reporting Persons pages and in Item 4 are incorporated by reference herein. (a) and (b) Items 7 through 11 and 13 of each of the cover pages of this Amendment No. 14 are incorporated herein by reference. The Ordinary Shares reported for each of the Adviser and the Adviser GP include 114,387,689 of the Ordinary Shares the Issuer reported that are beneficially owned through 8,799,053 ADS, 16,341 Ordinary Shares reported that are beneficially owned through 1,257 ADS held by each of Michael Goller and Ranjeev Krishana, full-time employees of the Adviser, as compensation for their previous service on the Board and 199,992 Ordinary Shares held by each of Michael Goller and Ranjeev Krishana in the form of 15,384 ADS received from the exercise of Exercised ADS Options as disclosed in Item 4. The Ordinary Shares reported for Julian C. Baker include 114,387,689 of the Ordinary Shares the Issuer reported that are beneficially owned through 8,799,053 ADS, 135,434 Ordinary Shares reported that are beneficially owned through 10,418 ADS directly held by Julian C. Baker, 175,708 Ordinary Shares reported that are beneficially owned through 13,516 ADS directly held by entities affiliated with Julian C. Baker, 144,508 Ordinary Shares reported that are beneficially owned through 11,116 ADS held by FBB3, 16,341 Ordinary Shares reported that are beneficially owned through 1,257 ADS held by each of Michael Goller and Ranjeev Krishana, full-time employees of the Adviser, as compensation for their previous service on the Board and 199,992 Ordinary Shares held by each of Michael Goller and Ranjeev Krishana in the form of 15,384 ADS received from the exercise of Exercised ADS Options as disclosed in Item 4. The Ordinary Shares reported for Felix J. Baker include 114,387,689 of the Ordinary Shares the Issuer reported that are beneficially owned through 8,799,053 ADS, 135,434 Ordinary Shares reported that are beneficially owned through 10,418 ADS directly held by Felix J. Baker, 175,708 Ordinary Shares reported that are beneficially owned through 13,516 ADS directly held by entities affiliated with Felix J. Baker, 144,508 Ordinary Shares reported that are beneficially owned through 11,116 ADS directly held by FBB3, 16,341 Ordinary Shares reported that are beneficially owned through 1,257 ADS held by each of Michael Goller and Ranjeev Krishana, full-time employees of the Adviser, as compensation for their previous service on the Board and 199,992 Ordinary Shares held by each of Michael Goller and Ranjeev Krishana in the form of 15,384 ADS received from the exercise of Exercised ADS Options as disclosed in Item 4. The Ordinary Shares reported for FBB3 include 144,508 of the Ordinary Shares the Issuer reported that are beneficially owned through 11,116 ADS. The percentage of beneficial ownership for each of the Reporting Persons reported herein, with the exception of FBB3 is based on 1,478,124,405 Ordinary Shares outstanding as of July 31, 2026 as reported in the Issuer's Form 10-Q filed with the Securities and Exchange Commission ("SEC") on August 5, 2026 plus 526,890 Ordinary Shares underlying 263,445 Share Options which were received by each of Michael Goller and Ranjeev Krishana, as compensation for their service on the Board, and 399,984 Ordinary Shares issued in the form of 30,768 ADS from the exercise of the Exercised ADS Options described in Item 4. The percentage of beneficial ownership for FBB3 reported herein is based on 1,478,124,405 Ordinary Shares outstanding as of July 31, 2026 as reported in the Issuer's Form 10-Q filed with the SEC on August 5, 2026 plus 399,984 Ordinary Shares issued in the form of 30,768 ADS from the exercise of the Exercised ADS Options described in Item 4.

Items 7 through 10 of each of the cover pages of this Amendment No. 14 are incorporated herein by reference. The disclosure in Item 5(a) is incorporated herein by reference. Set forth in Exhibit 99.1 is the aggregate number of Ordinary Shares of the Issuer directly held by the Funds, 114,387,689 of which are directly held by the Funds through 8,799,053 ADS, along with the percentage of the Issuer's outstanding Ordinary Shares such holdings represent. Julian C. Baker and Felix J. Baker each beneficially own 135,435 Ordinary Shares, 135,434 of which are held in the form of ADS. Entities affiliated with Julian C. Baker and Felix J. Baker each beneficially own 175,708 Ordinary Shares, 175,708 of which are held in the form of ADS. FBB3 holds 144,517 Ordinary Shares, 144,508 of which are held in the form of ADS. Ranjeev Krishana and Michael Goller each hold 199,992 Ordinary Shares held in the form of 15,384 ADS received from the exercise of Exercised ADS Options as disclosed in Item 4. Michael Goller and Ranjeev Krishana previously served on the Board. Felix J. Baker currently serves on the Board as a representative of the Funds. Michael Goller and Ranjeev Krishana each hold 263,445 Share Options received in connection with their previous service on the Board, which will remain exercisable until the earlier of: (i) the expiration date of the respective stock option as contemplated by such original Share Option grant; and (ii) for all granted options, three years from their final date of service pursuant to the acceleration of the expiration date upon the cessation of their service on the Board. Michael Goller and Ranjeev Krishana each hold 17,433 Share Options with an exercise price of $16.15 per Ordinary Share expiring 6/5/2028, 64,610 Share Options with an exercise price of $9.23 per Ordinary Share expiring 6/4/2029, 45,383 Share Options with an exercise price of $13.42 per Ordinary Share expiring 6/4/2029, 17,498 Share Options with an exercise price of $26.53 per Ordinary Share expiring 6/11/2029, 34,645 Share Options with an exercise price of $11.98 per Ordinary Share expiring 6/11/2029, 26,975 Share Options with an exercise price of $16.41 per Ordinary Share expiring 6/11/2029, 34,151 Share Options with an exercise price of $12.23 per Ordinary Share expiring 6/11/2029, and 22,750 Share Options with an exercise price of $18.19 per Ordinary Share expiring 6/11/2029. Michael Goller and Ranjeev Krishana hold 71,279 and 71,266 Ordinary Shares, respectively, 16,341 of which are held in the form of 1,257 ADS which were received upon the vesting of RSUs in connection with their previous service on the Board. On May 21, 2026, Michael Goller and Ranjeev Krishana each received 10,985 Ordinary Shares from the vesting of 10,985 RSUs of which on May 22, 2026, 2,743 Ordinary Shares at $23.8512 per share were sold for Michael Goller and 2,756 Ordinary Shares at $23.7905 per share were sold for Ranjeev Krishana in connection with the payment of mandatory Swiss withholding tax on the vesting of the RSUs. The policy of the Funds and the Adviser does not permit managing members of the Adviser GP or full-time employees of the Adviser to receive compensation for serving as directors of the Issuer, and the Funds are instead entitled to the pecuniary interest in any compensation received for their current or past service. The Adviser has voting and investment power over the RSUs, Share Options and Ordinary Shares underlying such Share Options and Ordinary Shares received from the exercise of Share Options received as director's compensation by Felix J. Baker for his current service on the Board and Michael Goller and Ranjeev Krishana received as director's compensation for their past service on the Board. The Adviser GP, and Felix J. Baker and Julian C. Baker as managing members of the Adviser GP, may be deemed to have the power to vote or direct the vote of and the power to dispose or direct the disposition of the Share Options, Ordinary Shares received from the exercise of Share Options and Ordinary Shares underlying such Share Options held by Felix J. Baker as director's compensation for his current service on the Board and Michael Goller and Ranjeev Krishana as director's compensation for their past service on the Board. The Adviser GP, Felix J. Baker and Julian C. Baker as managing members of the Adviser GP, and the Adviser may be deemed to be beneficial owners of securities of the Issuer directly held by the Funds. Julian C. Baker and Felix J. Baker are also the sole managers of FBB3 and by policy they do not transact in or vote the securities of the Issuer held by FBB3.

The information set forth in Item 4 is hereby incorporated by reference into this Item 5(c). Except as disclosed herein, none of the Reporting Persons or their affiliates has effected any other transactions in securities of the Issuer during the past 60 days.

Certain securities of the Issuer are held directly by 667, a limited partnership the sole general partner of which is Baker Biotech Capital, L.P., a limited partnership the sole general partner of which is Baker Biotech Capital (GP), LLC. Julian C. Baker and Felix J. Baker are the managing members of Baker Biotech Capital (GP), LLC. Certain securities of the Issuer are held directly by Life Sciences, a limited partnership the sole general partner of which is Baker Brothers Life Sciences Capital, L.P., a limited partnership the sole general partner of which is Baker Brothers Life Sciences Capital (GP), LLC. Julian C. Baker and Felix J. Baker are the managing members of Baker Brothers Life Sciences Capital (GP), LLC.

Not applicable.