Item 4 of the Statement is hereby amended and supplemented as follows: Subscription Agreement On December 4, 2025, the Company entered into a securities purchase agreement (the "Subscription Agreement") for a private investment in public equity ("PIPE") with certain institutional and accredited investors, including Fund II. The PIPE closed on December 8, 2025. Pursuant to the terms of the Subscription Agreement, Fund II purchased a total of 1,360,000 Ordinary Shares at a purchase price of $13.41 per share and Pre-Funded Warrants to purchase 131,434 Ordinary Shares at a purchase price of $13.409 per Pre-Funded Warrant, which represents the per share purchase price of the Ordinary Shares less the $0.001 per share exercise price for each Pre-Funded Warrant. The foregoing description of the Subscription Agreement does not purport to be complete and is qualified in its entirety by reference to the form of the Subscription Agreement, which is filed as Exhibit 99.2 hereto. Pre-Funded Warrants The Pre-Funded Warrants purchased by Fund II in the PIPE will be exercisable at any time after the date of issuance. A holder of Pre-Funded Warrants may not exercise the warrant if the holder, together with its affiliates, would beneficially own more than 9.99%, as applicable, of the number of Ordinary Shares outstanding immediately after giving effect to such exercise. A holder of Pre-Funded Warrants may increase or decrease this percentage to a percentage not in excess of 19.99% by providing notice to the Company. Any increase in the percentage will not be effective until the 61st day after such notice is delivered. The foregoing description of the Pre-Funded Warrants does not purport to be complete and is qualified in its entirety by reference to the form of Pre-Funded Warrant, which is filed as Exhibit 99.3 hereto. Registration Rights Agreement In connection with the PIPE, the Company and investors participating in the PIPE, including Fund II, entered into a registration rights agreement (the "Registration Rights Agreement"), which provides that the Company will register the resale of the Ordinary Shares and Pre-Funded Warrants sold in the PIPE. The Company is required to prepare and file an initial registration statement with the Securities and Exchange Commission no later than 30 days following the closing of the PIPE and to use its reasonable best efforts to have the initial registration statement and any amendment declared effective within 60 days thereafter, subject to certain exceptions. The Registration Rights Agreement also provides that the Company is required to indemnify the investors participating in the PIPE, their officers, directors, agents, partners, members, managers, stockholders, affiliates, investment advisers and employees under the registration statement from certain liabilities and pay all fees and expenses (excluding any legal fees of the selling holder(s), and any underwriting discounts and selling commissions) incident to the Company's obligations under the Registration Rights Agreement. The foregoing summary of the Registration Rights Agreement does not purport to be complete and is qualified in its entirety by reference to the form of Registration Rights Agreement, which is filed as Exhibit 99.4 hereto.